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Asked by anon-328813 on 9 Jun 2022.
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Ryan Devlin answered on 9 Jun 2022: last edited 9 Jun 2022 4:48 pm
The project that I am doing right now – looking at how a history of flu infection impacts your response to a tumour in the long term. There is a tremendous amount of freedom that comes with the project, and this PhD, and it is very invigorating being able to think/solve a problem by yourself.
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Karin Purshouse answered on 10 Jun 2022:
My PhD project is still a work in progress so instead I’ll pick a previous project about brain cancer that I did in the USA a few years ago. I learned how to use a technique called CRISPR that was very new at the time (basically it’s a way of making very precise changes to the DNA in a cell – the lead scientists behind this research won the Nobel prize recently!). I was making changes to brain cancer cells using CRISPR to make cells that had gene changes we know commonly occur in brain cancer.
I really liked the project because my boss was really dynamic and energising, my lab mates were really fun (I was the only Brit, and, unusually in science, the only girl in the lab – so I was really representing on two fronts!) and I learned loads of new stuff. My boss was the sort of person who really celebrated any success, no matter how small, and was so positive even when things were going badly. As I was living so far from home, I really appreciated how much I was made to feel a part of the team. The friends I made during that year abroad are still good friends of mine now! -
Chelsea Gerada answered on 15 Jun 2022:
Im currently working on how we can target metabolism or the energy sources cells use to survive to enhance immune system responses whilst also decreasing tumour growth. Some tumours are known to use different forms of energy processing from regular cells so this can be a way of selectively targeting tumour cells in therapy.
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Tammy Piper answered on 16 Jun 2022:
I got to try out different image analysis software, training them to count and group our breast cancer trial samples. That was quite fun and once I found a good one,. I have to validate the method and then we applied it to all our research shortening analysis time from 18 months per protein to 6 months.
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